FORMULATION AND EVALUATION OF MEDICATED CHEWING GUM PDFFORMULATION AND EVALUATION OF MEDICATED CHEWING GUM PDF

Abstract: The medicated chewing gum containing methyl prednisolone IP may be an excellent formulation to treat oral ulcer caused by the consumption of. An attempt has been made to formulate new chewing gum device for metaclopramide in the form of tablet. The new drug delivery system was obtained , at room. Formulation and evaluation of medicated chewing gum as antiplaque and antibacterial agent. S Vasudha Lakshmi1, Hemant KS Yadav1*, KP Mahesh2, Swati.

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Home Publications Conferences Register Contact. Abstract An attempt has been made to formulate new chewing gum for Dolasetron. In the present study, an attempt has been made to formulate the chewing gum of Dolasetron.

Pharmaceutica Analytica Acta Open Access. The aim of this study was to formulate chewing gum using chlorhexidine and chitosan and to prove its antibacterial and antiplaque properties effectively at low doses of chlorhexidine. Open Access Pharmaceutics Research Journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work e.

His Research Guide is Forjulation. Chitosan containing chewing gum has a greater antibacterial effect compared with gums containing only chlorhexidine. Formulation and evaluation of medicated chewing gum of Metaclopramide. Presently he is an M.

Formulation And Evaluation Of Medicated Chewing Gum Of Metaclopramide |

Pharmaceutical Sciences Journals Ann Jose ankara escort. Simple diffusion into the medium causes the release of only a small percentage of the drug contained in the medicated chewing gum, while the delivery of the major part of the dose occurs during mastication.

Chewing gums were prepared by using chlorhexidine and various proportions of gum base and chitosan. Ann Jose ankara escort. Guidelines Upcoming Special Issues. Naik H, Gupta S. The new drug delivery system was obtained, at room temperature conventional medicwted equipment.

Analysis of variance revealed significant differences between subjects receiving F1 and F5 for antiplaque activity. formulatino

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Paresh is having 3 International review articles and He is attended 1 National conferences in Solan H. Chlorohexidine Gluconate, Scholars Research Library, ; 2: Madan N, Rathnam A. To carry out in vivo study on humans double-blind, crossover clinical trial was conducted on 18 adult volunteers from Department of Oral Medicine and Radiology, JSS Dental College, Mysore.

Drug release from a dosage form is the critical chewinng in drug absorption and bioavailability, thus an experimental work has been designed to evaluate the efficiency of this kind of therapeutic system by verifying its capability to release the drug dose and by assessing the delivery of Metaclopramide for bypassing the hepatic first pass effect.

Simple diffusion into the medium evvaluation the release of only a small percentage of the drug contained in the medicated chewing gum, while the delivery of the major part of the dose occurs during mastication. Journal of Drug Delivery and Therapeutics7 4 Ezhumlai K, Rajalakshmi A.

A Modern Era of Drug Delivery, international research journal of pharmacy, ; 2 Drug release from a dosage form is the critical step in drug absorption and bioavailability, thus an experimental work has been designed to evaluate the efficiency of this kind of therapeutic system by verifying its capability to release the drug dose and by assessing the delivery of Dolasetron for forjulation the hepatic first pass effect.

The 5- Hydroxytrytryptamin Receptor Antagonist as Antiementis: The prepared gums were evaluated for physical parameters, compatibility studies, drug content, moisture content, stability studies and in vitro drug-release testing. Volume 7, Issue 4, July-August Agri and Aquaculture Journals Dr.

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From this study, we can conclude that the medicated chewing formulation can be a better choice in the coming years which provides several benefits and also benefits commercially. The test group administered chewing gums containing chlorhexidine, with and without the polymer, while the control group administered dummy chewing gums.

Hence, Metaclopramide chewing gum can be considered as a better formulation for the buccal drug delivery system, in which drug is absorbed buccally and reaches the systemic circulation via jugular vein. Motion Sickness Susceptibility, Autonomic Neuroscience: The dose of chlorhexidine can be reduced significantly when used along with chitosan.

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Chewing gumChitosanChlorhexidineDental Caries. Chewing gum, chitosan, chlorhexidine, dental caries. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 3.

Different formulations of chewing gum with varying concentration of plasticizers like glycerol and castor oil were formulated. An attempt has been made to formulate new chewing gum for Dolasetron.

Authors who publish with this journal agree to the following terms: The volunteers were visually examined for presence or absence of gingival erythema, gingival edema and gingival bleeding and the antibacterial activity was assessed by the reduction in bacterial count in the plaque samples. Authors are permitted and encouraged to post their work online e. An attempt has been made to formulate new chewing gum device for metaclopramide in the form of tablet. Announcements Editorial Board Indexing Contact.

Better consistency of formulation and faster release of drug in saliva was obtained with glycerol F IIIand Castor oil F II but castor oil shows optimum result against glycerol combination, which is formulation II. The in vivo studies on human volunteers were carried out for optimized formulation F5 containing chitosan and antibacterial agent which showed a better reduction in the bacterial count and gingival index.

The resulting chewing gum tablets comprise a gum core combined with fillers, antioxidants, coloring agent and plasticizers, which provide smooth appearance and flexibility during storage and chewing. In the present study, an attempt has been made to formulate the chewing gum of Metaclopramide.